Does oligometastatic breast cancer (OMBC) deserve a devoted therapy? Although some authors suggest multidisciplinary administration of OMBC with a healing intent, there isn’t any proof proving this technique useful within the absence of a randomized trial.
The present literature sheds little mild on OMBC. Incidence is unknown; information accessible are both out of date or biased; there isn’t any consensus on the definition of OMBC and metastatic websites, nor on essential imaging methods. However, sure proposals advantage consideration. Knowledge of eventual particular OMBC organic traits is restricted to circulating tumor cell (CTC) counts.
Given the information accessible for different cancers, research on microRNAs (miRNAs), circulating tumor DNA (ctDNA) and genomic alterations must be developed Finally, protected and efficient therapies do exist, however outcomes of randomized trials is not going to be accessible for a few years. Prospective observational cohort research must be carried out.

Engineering improved ethylene manufacturing: Leveraging programs Biology and adaptive laboratory evolution

Ethylene is a small hydrocarbon gasoline broadly used within the chemical trade. Annual worldwide manufacturing presently exceeds 150 million tons, producing appreciable quantities of CO2 contributing to local weather change. The want for a sustainable different is due to this fact crucial. Ethylene is natively produced by a number of completely different microorganisms, together with Pseudomonas syringae pv. phaseolicola through a course of catalyzed by the ethylene forming enzyme (EFE), subsequent heterologous expression of EFE has led to ethylene manufacturing in non-native bacterial hosts together with E. coli and cyanobacteria.
However, solubility of EFE and substrate availability stay charge limiting steps in organic ethylene manufacturing. We employed a mix of genome scale metabolic modelling, steady fermentation, and protein evolution to allow the accelerated improvement of a excessive effectivity ethylene producing E. coli pressure, yielding a 49-fold enhance in manufacturing, probably the most vital enchancment reported to this point.
Furthermore, we now have clearly demonstrated that this elevated yield resulted from metabolic variations that had been uniquely linked to the EFE enzyme (WT vs mutant). Our findings present a novel resolution to decontrol metabolic bottlenecks in key pathways, which will be readily utilized to handle different engineering challenges.

Machine studying in epigenomics: Insights into cancer biology and medication

The latest deluge of genome-wide applied sciences for the mapping of the epigenome and ensuing information in cancer samples has supplied the chance for gaining insights into and understanding the roles of epigenetic processes in cancer. However, the complexity, high-dimensionality, sparsity, and noise related to these information pose challenges for intensive integrative analyses.
Machine Learning (ML) algorithms are significantly suited to epigenomic information analyses attributable to their flexibility and capability to study underlying hidden constructions. We will focus on 4 overlapping however distinct main classes beneath ML: dimensionality discount, unsupervised strategies, supervised strategies, and deep studying (DL). We evaluate the popular use instances of these algorithms in analyses of cancer epigenomics information with the hope to offer an outline of how ML approaches can be utilized to discover elementary questions on the roles of epigenome in cancer biology and medication.

Myelin Biology

Myelin is a key evolutionary specialization and adaptation of vertebrates fashioned by the plasma membrane of glial cells, which insulate axons within the nervous system. Myelination not solely permits fast and environment friendly transmission of electrical impulses within the axon by reducing capacitance and rising resistance but in addition influences axonal metabolism and the plasticity of neural circuits. In this evaluate, we are going to concentrate on Schwann cells, the glial cells which kind myelin within the peripheral nervous system.
Here, we are going to describe the principle extrinsic and intrinsic alerts inducing Schwann cell differentiation and myelination and how myelin biogenesis is achieved. Finally, we will even focus on how the examine of human problems wherein molecules and pathways related for myelination are altered has enormously contributed to the present information on myelin biology.
Diagnosis, biology and epidemiology of oligometastatic breast cancer

The Genomics and Cell Biology of Host-Beneficial Intracellular Infections

Microbes acquire entry to eukaryotic cells as meals for bacteria-grazing protists, for host safety by microbe-killing immune cells, or for microbial profit when pathogens enter host cells to duplicate. But microbes can even acquire entry to a number cell and turn out to be an important-often required-beneficial companion. The oldest useful microbial infections are the traditional eukaryotic organelles now referred to as the mitochondrion and plastid. But quite a few different host-beneficial intracellular infections happen all through eukaryotes.
Here I evaluate the genomics and cell biology of these interactions with a concentrate on intracellular micro organism. The genomes of host-beneficial intracellular micro organism have options that span a beforehand unfilled hole between pathogens and organelles.

pAAV-DJ Vector

VPK-420-DJ 10 µg
EUR 530

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 530

pAAV-GFP Control Vector

AAV-400 10 µg
EUR 455

pAAV-Cre Control Vector

AAV-401 10 µg
EUR 679.2
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-LacZ Control Vector

AAV-402 10 µg
EUR 679.2
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-MCS Expression Vector

VPK-410 10 µg
EUR 530

pAAV-IRES-Neo Expression Vector

VPK-416 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-GFP Expression Vector

VPK-418 10 µg
EUR 530

pAAV-IRES-Bsd Expression Vector

VPK-419 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Puro Expression Vector

VPK-415 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Hygro Expression Vector

VPK-417 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-MCS Promoterless Expression Vector

VPK-411 10 µg
EUR 530

Green Kit. Baculovirus GFP vector.

K20 1 Kit
EUR 695
Description: Protein expression

ProGreen. Baculovirus GFP marker vector.

A1 25 ul
EUR 420
Description: Protein expression

pVL1393. General baculovirus plasmid vector.

B1 50 ul
EUR 340
Description: Protein expression

pAAV-RC6

PVT14647 2 ug
EUR 843.6

ProEasy. Vector for easy construction of recombinant baculoviruses.

A10S 25 ul
EUR 695
Description: Protein expression

pAcAB3. Baculovirus plasmid vector for expression of up to 3 proteins.

B2 50 ul
EUR 420
Description: Protein expression

pAB-bee. Baculovirus plasmid vector for secreted and transmembrane proteins.

B3 50 ul
EUR 495
Description: Protein expression

ProFold-PDI. Baculovirus chaperone vector for expression of cysteine-rich proteins.

A7 25 ul
EUR 830
Description: Protein expression

ProFold-C1. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins.

A2 25 ul
EUR 830
Description: Protein expression

ProFold-C2. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins.

A3 25 ul
EUR 830
Description: Protein expression

ProFold-ER1. Baculovirus chaperone vector for expression of secreted and membrane proteins.

A4 25 ul
EUR 830
Description: Protein expression

pAAV- RC

PVT2103 2 ug
EUR 289.2

C1 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins.

K21 1 Kit
EUR 995
Description: Protein expression

C2 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins.

K22 1 Kit
EUR 995
Description: Protein expression

ER1 Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins.

K23 1 Kit
EUR 995
Description: Protein expression

ER1-bee Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins.

K24 1 Kit
EUR 995
Description: Protein expression

pAAV- MCS Plasmid

PVT2102 2 ug
EUR 289.2

pAAV-CAG-GFP

PVT17666 2 ug
EUR 409.2

pAAV-fNPY-GFP

PVT14636 2 ug
EUR 718.8

pAAV- IRES- ZsGreen1

PVT11044 2 ug
EUR 361.2

pAAV- ZsGreen1- shRNA

PVT11045 2 ug
EUR 444

pAAV-RSV-SpCas9

PVT17629 2 ug
EUR 360

pAAV- IRES- hrGFP Plasmid

PVT2104 2 ug
EUR 319.2

pAAV-EF1a-DIO-mCherry

PVT17841 2 ug
EUR 360

pAAV- CMV- mCherry- U6- sgRNA

PVT11046 2 ug
EUR 361.2

pAAV-hSyn-eNpHR 3.0-EYFP

PVT19063 2 ug
EUR 309.6

pAAV-hSyn-hChR2(H134R)-mCherry

PVT19026 2 ug
EUR 309.6

pAAV-EF1a-DIO-hM3D(Gq)-mCherry

PVT17847 2 ug
EUR 360

pAAV-MCS-Ppargc1a-m-FLAG-HA

PVT18341 2 ug
EUR 360

pAB-bee-FH. FLAG and His tagging of secreted and transmembrane proteins in baculovirus system.

B3FH 50 ul
EUR 495
Description: Protein expression

pAB-bee-8xHis. His tagging of secreted and transmembrane proteins in baculovirus system.

B3H 50 ul
EUR 495
Description: Protein expression

pAB-6xHis. His tagging of cytoplasmic and nuclear proteins in baculovirus system.

B4 50 ul
EUR 295
Description: Protein expression

pAB-GST. GST tagging of cytoplasmic and nuclear proteins in baculovirus system.

B5 50 ul
EUR 295
Description: Protein expression

pAB-MBP. MBP tagging of cytoplasmic and nuclear proteins in baculovirus system.

B6 50 ul
EUR 395
Description: Protein expression

pAB-6xHis-MBP. His and MBP tagging of cytoplasmic and nuclear proteins in baculovirus system.

B7 50 ul
EUR 495
Description: Protein expression

pVL-GFP. GFP tagging of cytoplasmic and nuclear proteins in baculovirus system.

B8 50 ul
EUR 395
Description: Protein expression

pVL-FH. Flag and His tagging of cytoplasmic and nuclear proteins in baculovirus system.

B9 50 ul
EUR 295
Description: Protein expression

BV-p53. Recombinant baculovirus expressing p53 (wt).

BV53 1 ml
EUR 980
Description: Drug discovery, Transcription factors, baculovirus

NC (negative control baculovirus)

C13 1 ml
EUR 195
Description: Protein expression

GC (green control baculovirus expressing GFP)

C14 1 ml
EUR 195
Description: Protein expression

GCP (green control plasmid for GFP expression)

C15 50 ul
EUR 145
Description: Protein expression

BV-ADRA1D. Recombinant baculovirus expressing Adrenergic Receptor alpha 1D.

GA11 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA2A. Recombinant baculovirus expressing Adrenergic Receptor alpha 2A.

GA15 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA2C. Recombinant baculovirus expressing Adrenergic Receptor alpha 2C.

GA19 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRB2. Recombinant baculovirus expressing Adrenergic Receptor beta 2

GA23 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA1A. Recombinant baculovirus expressing Adrenergic Receptor alpha 1A (ADRA1A)

GA3 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA1B. Recombinant baculovirus expressing Adrenergic Receptor alpha 1B.

GA7 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-AGTR1. Recombinant baculovirus expressing angiotensin II receptor (AGTR1).

GAT1 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-DRD1. Recombinant baculovirus expressing Dopamine receptor 1 (DRD1).

GD3 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-DRD2. Recombinant baculovirus expressing Dopamine receptor 1 (DRD2).

GD5 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH1. Recombinant baculovirus expressing Histamine receptor (HRH1).

GH41 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH2. Recombinant baculovirus expressing Histamine receptor (HRH2).

GH45 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH3. Recombinant baculovirus expressing Histamine receptor (HRH3).

GH49 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH4. Recombinant baculovirus expressing Histamine receptor (HRH4).

GH53 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-CHRM1. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 1 (CHRM1).

GM1 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-CHRM2. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 2 (CHRM2).

GM5 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1A.

GS27 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1B.

GS31 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1D. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1D.

GS35 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1F. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1F.

GS37 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR2A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2A.

GS39 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR2B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2B.

GS43 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR2C. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2C.

GS47 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR5A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 5A.

GS51 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR7B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 7B.

GS55 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

FoldHelper-57P. Recombinant baculovirus expressing ERp57 and PDI.

H17 1 ml
EUR 295
Description: Protein expression

FoldHelper-37. Recombinant baculovirus expressing cdc37.

H18 1 ml
EUR 395
Description: Protein expression

FoldHelper-ER3. Recombinant baculovirus expressing human ER chaperones.

H6 2 ml
EUR 695
Description: Protein expression

Controls Kit. Baculovirus controls.

K26 1 Kit
EUR 295
Description: Protein expression

THRB-LBD. Purified GST-tagged human Thyroid hormone receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1A2 50 ug
EUR 660
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARA-LBD. Purified GST-tagged human Retinoic acid receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B1 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARB-LBD. Purified GST-tagged human Retinoic acid receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B2 50 ug
EUR 420
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARG-LBD. Purified GST-tagged human Retinoic acid receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B3 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PPARG-LBD. Purified GST-tagged human Peroxisome proliferator-activated receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1C3 50 ug
EUR 720
Description: Drug discovery, Nuclear receptors, purified recombinant protein

LXRB-LBD. Purified GST-tagged human Liver X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1H2 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

LXRA-LBD. Purified GST-tagged human Liver X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1H3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

FXR-LBD. Purified GST-tagged human Farnesoid X receptor ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1H4 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRA-LBD. Purified GST-tagged human Retinoid X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N2B1 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRB-LBD. Purified GST-tagged human Retinoid X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N2B2 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRG-LBD. Purified GST-tagged human Retinoid X receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N2B3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ERb-LBD. Purified GST-tagged human Estrogen receptor beta LBD. Applications: Ligand-binding and coregulator displacement assays.

N3A2 50 ug
EUR 495
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRA-LBD. Purified GST-tagged human Estrogen-related receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N3B1 50 ug
EUR 980
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRB-LBD. Purified GST-tagged human Estrogen-related receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N3B2 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRG-LBD. Purified GST-tagged human Estrogen-related receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N3B3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

BV-Tau412. Recombinant baculovirus expressing 412 aa Tau isoform.

PD13 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau412TR. Recombinant baculovirus expressing 412 aa Tau isoform. T39-R mutant.

PD14 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau412KE. Recombinant baculovirus expressing 412 aa Tau isoform. K267-E mutant.

PD15 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Synuclein. Recombinant baculovirus expressing alpha synuclein.

PD17 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Syn-GFP. Recombinant baculovirus expressing alpha synuclein-GFP fusion.

PD21 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-SOD1. Recombinant baculovirus expressing SOD1.

PD25 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-SOD1-GFP. Recombinant baculovirus expressing SOD1-GFP fusion.

PD29 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau352. Recombinant baculovirus expressing 352 aa Tau isoform.

PD3 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau383. Recombinant baculovirus expressing 383 aa Tau isoform.

PD7 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau381. Recombinant baculovirus expressing 381 aa Tau isoform.

PD9 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-PR-LBD. Recombinant baculovirus expressing Progesterone receptor LBD.

S15 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-MR-LBD. Recombinant baculovirus expressing Mineralocorticoid receptor LBD.

S27 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

MR-LBD. Purified GST-tagged MR LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

S28 50 ug
EUR 1240
Description: Drug discovery, Nuclear receptors, purified recombinant protein

BV-GR-LBD. Recombinant baculovirus expressing Glucocorticoid receptor LBD.

S33 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-GR. Recombinant baculovirus expressing Glucocorticoid receptor.

S35 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-PXR-LBD. Recombinant baculovirus expressing Pregnane X receptor LBD.

S36 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-AhR. Recombinant baculovirus expressing Aryl hydrocarbon receptor LBD.

S41 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

AhR-LBD. Purified GST-tagged human Arylhydrocarbon receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SAh90 50 ug
EUR 980
Description: Drug discovery, Nuclear receptors, purified recombinant protein

CAR. Purified GST-tagged human Constitutive andristane receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SC90 50 ug
EUR 1100
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ERa-LBD (Hsp90). Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SEa90 50 ug
EUR 1100
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ERb-LBD (Hsp90). Purified GST-tagged human Estrogen receptor beta LBD in complex with Hsp90. Applications: ligand-binding and coregulator displacement studies.

SEb90 50 ug
EUR 760
Description: Drug discovery, Nuclear receptors, purified recombinant protein

GR-LBD. GR-LBD. Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. For ligand-binding and coregulator displacement studies.

SG90 50 ug
EUR 1240
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PR-LBD. Purified GST-tagged human Progesterone receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SP90 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PXR-LBD. Purified GST-tagged human Pregnane X receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SPX90 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ProFectin. Transfection reagent for insect cells.

T10 50 ul
EUR 160
Description: Transfection

ProFectin. Transfection reagent for insect cells.

T20 100 ul
EUR 295
Description: Transfection

pAAVS1-SA-T2A-Neo-MCS Donor Vector

AC2002 10 μg
EUR 665

pAAVK-EF1α -MCS AAVanced Cloning and Expression Vector

AAV502A-1 10 ug
EUR 614

pAAVS1-SA-T2A-Neo-CAG-MCS-SV40pA Donor Vector

AC2302 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-CAG-MCS-SV40pA Donor Vector

AC2301 10 μg
EUR 665

pAAVS1-SA-T2A-HygR-CAG-MCS-SV40pA Donor Vector

AC2303 10 μg
EUR 665

pAAVS1-SA-T2A-Neo-SV40pA-MCS-SFFV Donor Vector

AC2402 10 μg
EUR 665

pAAVS1-SA-T2A-Neo-CAG-dCas9-VPR-pA Donor Vector

AC8302 10 μg
EUR 805

pAAVS1-SA-T2A-Neo-CAG-dCas9-KRAB-pA Donor Vector

AC7302 10 μg
EUR 805

pAAVS1-SA-T2A-Neo-CAG-EGFP-SV40pA Control Donor Vector

AC9312 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-CAG-EGFP-SV40pA Control Donor Vector

AC9311 10 μg
EUR 665

pAAVK-EF1α -MCS-T2A-EGFP AAVanced Cloning and Expression Vector

AAV526A-1 10 ug
EUR 614

pAAVK-EF1α -MCS-T2A-Puro AAVanced Cloning and Expression Vector

AAV527A-1 10 ug
EUR 614

pAAVK-EF1α –MCS-T2A-mRFP AAVanced Cloning and Expression Vector

AAV528A-1 10 ug
EUR 614

pAAVS1-SA-T2A-Puro-SV40pA-EGFP-SFFV Control Donor Vector

AC9411 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-CAG-copGFP-SV40pA Control Donor Vector

AC9321 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-SV40pA-copGFP-SFFV Control Donor Vector

AC9421 10 μg
EUR 665

pAAVK-EF1α-MCS1-CMV-MCS2 AAVanced Cloning and Expression Vector

AAV503A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-EGFP AAVanced Cloning and Expression Vector

AAV536A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-Puro AAVanced Cloning and Expression Vector

AAV537A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-mRFP AAVanced Cloning and Expression Vector

AAV538A-1 10 ug
EUR 614

AAVS1 Safe Harbor cDNA/miRNA Donor Vector [pAAVS1D-PGK.MCS-EF1a.copGFPpuro]

GE602A-1 10 ug
EUR 1190

pAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-VPR-pA Donor Vector

AI8902 10 μg
EUR 875

pAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-KRAB-pA Donor Vector

AI7902 10 μg
EUR 875

pAAVS1-SA-T2A-Puro-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector

AI3901 10 μg
EUR 875

pAAVS1-SA-T2A-Neo-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector

AI3902 10 μg
EUR 875

pAAVS1-SA-T2A-HygR-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector

AI3903 10 μg
EUR 875

AAVS1 Safe Harbor Positive Control Donor Vector [pAAVS1D-CMV.RFP-EF1a.copGFPpuro]

GE603A-1 10 ug
EUR 1190

pAAVS1-SA-T2A-Puro-CAG-EGFP-SV40pA-SV40pA-MCS-SFFV Donor Vector

AC4411 10 μg
EUR 665

Rc3h2 ORF Vector (Rat) (pORF)

ORF074641 1.0 ug DNA
EUR 607.2

RC3H2 ORF Vector (Human) (pORF)

ORF008684 1.0 ug DNA
EUR 114

RC3H1 ORF Vector (Human) (pORF)

ORF028827 1.0 ug DNA
EUR 486

Rc3h1 ORF Vector (Mouse) (pORF)

ORF055784 1.0 ug DNA
EUR 607.2

Rc3h2 ORF Vector (Mouse) (pORF)

ORF055785 1.0 ug DNA
EUR 607.2

RC3H1-IT1 ORF Vector (Human) (pORF)

ORF028828 1.0 ug DNA Ask for price

PAAF1 ORF Vector (Human) (pORF)

ORF007465 1.0 ug DNA
EUR 114

PAAF1 ORF Vector (Human) (pORF)

ORF007466 1.0 ug DNA
EUR 114

pAAV2- 8

PVT11048 2 ug
EUR 361.2

pAAV5

PVT11596 2 ug
EUR 364.8

RC3H2 Protein Vector (Rat) (pPM-C-HA)

PV298564 500 ng
EUR 1399.2

RC3H2 Protein Vector (Rat) (pPB-C-His)

PV298562 500 ng
EUR 1399.2

RC3H2 Protein Vector (Rat) (pPB-N-His)

PV298563 500 ng
EUR 1399.2

RC3H2 Protein Vector (Rat) (pPM-C-His)

PV298565 500 ng
EUR 1399.2

RC3H2 Protein Vector (Human) (pPM-C-HA)

PV034735 500 ng
EUR 394.8

RC3H1 Protein Vector (Human) (pPM-C-HA)

PV115308 500 ng
EUR 973.2

RC3H1 Protein Vector (Mouse) (pPM-C-HA)

PV223136 500 ng
EUR 1278

RC3H2 Protein Vector (Mouse) (pPM-C-HA)

PV223140 500 ng
EUR 1278

RC3H2 Protein Vector (Human) (pPB-C-His)

PV034733 500 ng
EUR 394.8

RC3H2 Protein Vector (Human) (pPB-N-His)

PV034734 500 ng
EUR 394.8

RC3H2 Protein Vector (Human) (pPM-C-His)

PV034736 500 ng
EUR 394.8

RC3H1 Protein Vector (Human) (pPB-C-His)

PV115306 500 ng
EUR 973.2

RC3H1 Protein Vector (Human) (pPB-N-His)

PV115307 500 ng
EUR 973.2

RC3H1 Protein Vector (Human) (pPM-C-His)

PV115309 500 ng
EUR 973.2

RC3H1 Protein Vector (Mouse) (pPB-C-His)

PV223134 500 ng
EUR 1278

RC3H1 Protein Vector (Mouse) (pPB-N-His)

PV223135 500 ng
EUR 1278

RC3H1 Protein Vector (Mouse) (pPM-C-His)

PV223137 500 ng
EUR 1278

RC3H2 Protein Vector (Mouse) (pPB-C-His)

PV223138 500 ng
EUR 1278

RC3H2 Protein Vector (Mouse) (pPB-N-His)

PV223139 500 ng
EUR 1278

RC3H2 Protein Vector (Mouse) (pPM-C-His)

PV223141 500 ng
EUR 1278

RC3H1-IT1 Protein Vector (Human) (pPM-C-HA)

PV115312 500 ng Ask for price

RC3H1-IT1 Protein Vector (Human) (pPB-C-His)

PV115310 500 ng Ask for price

RC3H1-IT1 Protein Vector (Human) (pPB-N-His)

PV115311 500 ng Ask for price

RC3H1-IT1 Protein Vector (Human) (pPM-C-His)

PV115313 500 ng Ask for price

PAAF1 Protein Vector (Human) (pPM-C-HA)

PV029859 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPM-C-HA)

PV029863 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPB-C-His)

PV029857 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPB-N-His)

PV029858 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPM-C-His)

PV029860 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPB-C-His)

PV029861 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPB-N-His)

PV029862 500 ng
EUR 394.8

PAAF1 Protein Vector (Human) (pPM-C-His)

PV029864 500 ng
EUR 394.8

RC3H2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV639829 1.0 ug DNA
EUR 1626

RC3H2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV639833 1.0 ug DNA
EUR 1626

RC3H2 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV639834 1.0 ug DNA
EUR 1626

pAAVS1- P- CAG- GFP

PVT10997 2 ug
EUR 361.2

RC3H1-IT1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV742619 1.0 ug DNA Ask for price

RC3H1-IT1 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV742623 1.0 ug DNA Ask for price

pAAVS1-P-MCS

PVT12296 2 ug
EUR 843.6

RC3H1-IT1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV742624 1.0 ug DNA Ask for price

PAAF1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713073 1.0 ug DNA
EUR 379.2
Host cell variations to permit the intracellular persistence of useful micro organism are discovered together with proof for the microbial manipulation of host cells, however the mobile mechanisms of useful bacterial infections usually are not nicely understood. Expected closing on-line publication date for the Annual Review of Cell and Developmental Biology, Volume 37 is October 2021.

Leave a Reply

Your email address will not be published. Required fields are marked *