Does oligometastatic breast cancer (OMBC) deserve a devoted therapy? Although some authors suggest multidisciplinary administration of OMBC with a healing intent, there isn’t any proof proving this technique useful within the absence of a randomized trial.
The present literature sheds little mild on OMBC. Incidence is unknown; information accessible are both out of date or biased; there isn’t any consensus on the definition of OMBC and metastatic websites, nor on essential imaging methods. However, sure proposals advantage consideration. Knowledge of eventual particular OMBC organic traits is restricted to circulating tumor cell (CTC) counts.
Given the information accessible for different cancers, research on microRNAs (miRNAs), circulating tumor DNA (ctDNA) and genomic alterations must be developed Finally, protected and efficient therapies do exist, however outcomes of randomized trials is not going to be accessible for a few years. Prospective observational cohort research must be carried out.
Engineering improved ethylene manufacturing: Leveraging programs Biology and adaptive laboratory evolution
Ethylene is a small hydrocarbon gasoline broadly used within the chemical trade. Annual worldwide manufacturing presently exceeds 150 million tons, producing appreciable quantities of CO2 contributing to local weather change. The want for a sustainable different is due to this fact crucial. Ethylene is natively produced by a number of completely different microorganisms, together with Pseudomonas syringae pv. phaseolicola through a course of catalyzed by the ethylene forming enzyme (EFE), subsequent heterologous expression of EFE has led to ethylene manufacturing in non-native bacterial hosts together with E. coli and cyanobacteria.
However, solubility of EFE and substrate availability stay charge limiting steps in organic ethylene manufacturing. We employed a mix of genome scale metabolic modelling, steady fermentation, and protein evolution to allow the accelerated improvement of a excessive effectivity ethylene producing E. coli pressure, yielding a 49-fold enhance in manufacturing, probably the most vital enchancment reported to this point.
Furthermore, we now have clearly demonstrated that this elevated yield resulted from metabolic variations that had been uniquely linked to the EFE enzyme (WT vs mutant). Our findings present a novel resolution to decontrol metabolic bottlenecks in key pathways, which will be readily utilized to handle different engineering challenges.
Machine studying in epigenomics: Insights into cancer biology and medication
The latest deluge of genome-wide applied sciences for the mapping of the epigenome and ensuing information in cancer samples has supplied the chance for gaining insights into and understanding the roles of epigenetic processes in cancer. However, the complexity, high-dimensionality, sparsity, and noise related to these information pose challenges for intensive integrative analyses.
Machine Learning (ML) algorithms are significantly suited to epigenomic information analyses attributable to their flexibility and capability to study underlying hidden constructions. We will focus on 4 overlapping however distinct main classes beneath ML: dimensionality discount, unsupervised strategies, supervised strategies, and deep studying (DL). We evaluate the popular use instances of these algorithms in analyses of cancer epigenomics information with the hope to offer an outline of how ML approaches can be utilized to discover elementary questions on the roles of epigenome in cancer biology and medication.
Myelin Biology
Myelin is a key evolutionary specialization and adaptation of vertebrates fashioned by the plasma membrane of glial cells, which insulate axons within the nervous system. Myelination not solely permits fast and environment friendly transmission of electrical impulses within the axon by reducing capacitance and rising resistance but in addition influences axonal metabolism and the plasticity of neural circuits. In this evaluate, we are going to concentrate on Schwann cells, the glial cells which kind myelin within the peripheral nervous system.
Here, we are going to describe the principle extrinsic and intrinsic alerts inducing Schwann cell differentiation and myelination and how myelin biogenesis is achieved. Finally, we will even focus on how the examine of human problems wherein molecules and pathways related for myelination are altered has enormously contributed to the present information on myelin biology.
The Genomics and Cell Biology of Host-Beneficial Intracellular Infections
Microbes acquire entry to eukaryotic cells as meals for bacteria-grazing protists, for host safety by microbe-killing immune cells, or for microbial profit when pathogens enter host cells to duplicate. But microbes can even acquire entry to a number cell and turn out to be an important-often required-beneficial companion. The oldest useful microbial infections are the traditional eukaryotic organelles now referred to as the mitochondrion and plastid. But quite a few different host-beneficial intracellular infections happen all through eukaryotes.
Here I evaluate the genomics and cell biology of these interactions with a concentrate on intracellular micro organism. The genomes of host-beneficial intracellular micro organism have options that span a beforehand unfilled hole between pathogens and organelles.
pAAV-Cre Control Vector |
AAV-401 |
Cell Biolabs |
10 µg |
EUR 679.2 |
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control. |
pAAV-LacZ Control Vector |
AAV-402 |
Cell Biolabs |
10 µg |
EUR 679.2 |
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control. |
pAAV-MCS Expression Vector |
VPK-410 |
Cell Biolabs |
10 µg |
EUR 530 |
pAAV-IRES-Neo Expression Vector |
VPK-416 |
Cell Biolabs |
10 µg |
EUR 776.4 |
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV. |
pAAV-IRES-GFP Expression Vector |
VPK-418 |
Cell Biolabs |
10 µg |
EUR 530 |
pAAV-IRES-Bsd Expression Vector |
VPK-419 |
Cell Biolabs |
10 µg |
EUR 776.4 |
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV. |
pAAV-IRES-Puro Expression Vector |
VPK-415 |
Cell Biolabs |
10 µg |
EUR 776.4 |
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV. |
pAAV-IRES-Hygro Expression Vector |
VPK-417 |
Cell Biolabs |
10 µg |
EUR 776.4 |
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV. |
pAAV-MCS Promoterless Expression Vector |
VPK-411 |
Cell Biolabs |
10 µg |
EUR 530 |
Green Kit. Baculovirus GFP vector. |
K20 |
AB Vector LLC |
1 Kit |
EUR 695 |
|
Description: Protein expression |
ProGreen. Baculovirus GFP marker vector. |
A1 |
AB Vector LLC |
25 ul |
EUR 420 |
|
Description: Protein expression |
pVL1393. General baculovirus plasmid vector. |
B1 |
AB Vector LLC |
50 ul |
EUR 340 |
|
Description: Protein expression |
ProEasy. Vector for easy construction of recombinant baculoviruses. |
A10S |
AB Vector LLC |
25 ul |
EUR 695 |
|
Description: Protein expression |
pAcAB3. Baculovirus plasmid vector for expression of up to 3 proteins. |
B2 |
AB Vector LLC |
50 ul |
EUR 420 |
|
Description: Protein expression |
pAB-bee. Baculovirus plasmid vector for secreted and transmembrane proteins. |
B3 |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
ProFold-PDI. Baculovirus chaperone vector for expression of cysteine-rich proteins. |
A7 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
ProFold-C1. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins. |
A2 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
ProFold-C2. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins. |
A3 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
ProFold-ER1. Baculovirus chaperone vector for expression of secreted and membrane proteins. |
A4 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
C1 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins. |
K21 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
C2 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins. |
K22 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
ER1 Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins. |
K23 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
ER1-bee Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins. |
K24 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
pAB-bee-FH. FLAG and His tagging of secreted and transmembrane proteins in baculovirus system. |
B3FH |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
pAB-bee-8xHis. His tagging of secreted and transmembrane proteins in baculovirus system. |
B3H |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
pAB-6xHis. His tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B4 |
AB Vector LLC |
50 ul |
EUR 295 |
|
Description: Protein expression |
pAB-GST. GST tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B5 |
AB Vector LLC |
50 ul |
EUR 295 |
|
Description: Protein expression |
pAB-MBP. MBP tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B6 |
AB Vector LLC |
50 ul |
EUR 395 |
|
Description: Protein expression |
pAB-6xHis-MBP. His and MBP tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B7 |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
pVL-GFP. GFP tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B8 |
AB Vector LLC |
50 ul |
EUR 395 |
|
Description: Protein expression |
pVL-FH. Flag and His tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B9 |
AB Vector LLC |
50 ul |
EUR 295 |
|
Description: Protein expression |
BV-p53. Recombinant baculovirus expressing p53 (wt). |
BV53 |
AB Vector LLC |
1 ml |
EUR 980 |
|
Description: Drug discovery, Transcription factors, baculovirus |
NC (negative control baculovirus) |
C13 |
AB Vector LLC |
1 ml |
EUR 195 |
|
Description: Protein expression |
GC (green control baculovirus expressing GFP) |
C14 |
AB Vector LLC |
1 ml |
EUR 195 |
|
Description: Protein expression |
GCP (green control plasmid for GFP expression) |
C15 |
AB Vector LLC |
50 ul |
EUR 145 |
|
Description: Protein expression |
BV-ADRA1D. Recombinant baculovirus expressing Adrenergic Receptor alpha 1D. |
GA11 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA2A. Recombinant baculovirus expressing Adrenergic Receptor alpha 2A. |
GA15 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA2C. Recombinant baculovirus expressing Adrenergic Receptor alpha 2C. |
GA19 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRB2. Recombinant baculovirus expressing Adrenergic Receptor beta 2 |
GA23 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA1A. Recombinant baculovirus expressing Adrenergic Receptor alpha 1A (ADRA1A) |
GA3 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA1B. Recombinant baculovirus expressing Adrenergic Receptor alpha 1B. |
GA7 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-AGTR1. Recombinant baculovirus expressing angiotensin II receptor (AGTR1). |
GAT1 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-DRD1. Recombinant baculovirus expressing Dopamine receptor 1 (DRD1). |
GD3 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-DRD2. Recombinant baculovirus expressing Dopamine receptor 1 (DRD2). |
GD5 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH1. Recombinant baculovirus expressing Histamine receptor (HRH1). |
GH41 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH2. Recombinant baculovirus expressing Histamine receptor (HRH2). |
GH45 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH3. Recombinant baculovirus expressing Histamine receptor (HRH3). |
GH49 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH4. Recombinant baculovirus expressing Histamine receptor (HRH4). |
GH53 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-CHRM1. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 1 (CHRM1). |
GM1 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-CHRM2. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 2 (CHRM2). |
GM5 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1A. |
GS27 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1B. |
GS31 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1D. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1D. |
GS35 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1F. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1F. |
GS37 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR2A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2A. |
GS39 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR2B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2B. |
GS43 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR2C. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2C. |
GS47 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR5A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 5A. |
GS51 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR7B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 7B. |
GS55 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
FoldHelper-57P. Recombinant baculovirus expressing ERp57 and PDI. |
H17 |
AB Vector LLC |
1 ml |
EUR 295 |
|
Description: Protein expression |
FoldHelper-37. Recombinant baculovirus expressing cdc37. |
H18 |
AB Vector LLC |
1 ml |
EUR 395 |
|
Description: Protein expression |
FoldHelper-ER3. Recombinant baculovirus expressing human ER chaperones. |
H6 |
AB Vector LLC |
2 ml |
EUR 695 |
|
Description: Protein expression |
Controls Kit. Baculovirus controls. |
K26 |
AB Vector LLC |
1 Kit |
EUR 295 |
|
Description: Protein expression |
THRB-LBD. Purified GST-tagged human Thyroid hormone receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1A2 |
AB Vector LLC |
50 ug |
EUR 660 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RARA-LBD. Purified GST-tagged human Retinoic acid receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1B1 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RARB-LBD. Purified GST-tagged human Retinoic acid receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1B2 |
AB Vector LLC |
50 ug |
EUR 420 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RARG-LBD. Purified GST-tagged human Retinoic acid receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1B3 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
PPARG-LBD. Purified GST-tagged human Peroxisome proliferator-activated receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1C3 |
AB Vector LLC |
50 ug |
EUR 720 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
LXRB-LBD. Purified GST-tagged human Liver X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1H2 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
LXRA-LBD. Purified GST-tagged human Liver X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1H3 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
FXR-LBD. Purified GST-tagged human Farnesoid X receptor ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1H4 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RXRA-LBD. Purified GST-tagged human Retinoid X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N2B1 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RXRB-LBD. Purified GST-tagged human Retinoid X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N2B2 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RXRG-LBD. Purified GST-tagged human Retinoid X receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N2B3 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ERb-LBD. Purified GST-tagged human Estrogen receptor beta LBD. Applications: Ligand-binding and coregulator displacement assays. |
N3A2 |
AB Vector LLC |
50 ug |
EUR 495 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ESRRA-LBD. Purified GST-tagged human Estrogen-related receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N3B1 |
AB Vector LLC |
50 ug |
EUR 980 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ESRRB-LBD. Purified GST-tagged human Estrogen-related receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N3B2 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ESRRG-LBD. Purified GST-tagged human Estrogen-related receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N3B3 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
BV-Tau412. Recombinant baculovirus expressing 412 aa Tau isoform. |
PD13 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau412TR. Recombinant baculovirus expressing 412 aa Tau isoform. T39-R mutant. |
PD14 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau412KE. Recombinant baculovirus expressing 412 aa Tau isoform. K267-E mutant. |
PD15 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Synuclein. Recombinant baculovirus expressing alpha synuclein. |
PD17 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Syn-GFP. Recombinant baculovirus expressing alpha synuclein-GFP fusion. |
PD21 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-SOD1. Recombinant baculovirus expressing SOD1. |
PD25 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-SOD1-GFP. Recombinant baculovirus expressing SOD1-GFP fusion. |
PD29 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau352. Recombinant baculovirus expressing 352 aa Tau isoform. |
PD3 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau383. Recombinant baculovirus expressing 383 aa Tau isoform. |
PD7 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau381. Recombinant baculovirus expressing 381 aa Tau isoform. |
PD9 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-PR-LBD. Recombinant baculovirus expressing Progesterone receptor LBD. |
S15 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-MR-LBD. Recombinant baculovirus expressing Mineralocorticoid receptor LBD. |
S27 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
MR-LBD. Purified GST-tagged MR LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
S28 |
AB Vector LLC |
50 ug |
EUR 1240 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
BV-GR-LBD. Recombinant baculovirus expressing Glucocorticoid receptor LBD. |
S33 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-GR. Recombinant baculovirus expressing Glucocorticoid receptor. |
S35 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-PXR-LBD. Recombinant baculovirus expressing Pregnane X receptor LBD. |
S36 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-AhR. Recombinant baculovirus expressing Aryl hydrocarbon receptor LBD. |
S41 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
AhR-LBD. Purified GST-tagged human Arylhydrocarbon receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SAh90 |
AB Vector LLC |
50 ug |
EUR 980 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
CAR. Purified GST-tagged human Constitutive andristane receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SC90 |
AB Vector LLC |
50 ug |
EUR 1100 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ERa-LBD (Hsp90). Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SEa90 |
AB Vector LLC |
50 ug |
EUR 1100 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ERb-LBD (Hsp90). Purified GST-tagged human Estrogen receptor beta LBD in complex with Hsp90. Applications: ligand-binding and coregulator displacement studies. |
SEb90 |
AB Vector LLC |
50 ug |
EUR 760 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
GR-LBD. GR-LBD. Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. For ligand-binding and coregulator displacement studies. |
SG90 |
AB Vector LLC |
50 ug |
EUR 1240 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
PR-LBD. Purified GST-tagged human Progesterone receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SP90 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
PXR-LBD. Purified GST-tagged human Pregnane X receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SPX90 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ProFectin. Transfection reagent for insect cells. |
T10 |
AB Vector LLC |
50 ul |
EUR 160 |
|
Description: Transfection |
ProFectin. Transfection reagent for insect cells. |
T20 |
AB Vector LLC |
100 ul |
EUR 295 |
|
Description: Transfection |
pAAVS1-SA-T2A-Neo-MCS Donor Vector |
AC2002 |
ALSTEM |
10 μg |
EUR 665 |
pAAVK-EF1α -MCS AAVanced Cloning and Expression Vector |
AAV502A-1 |
SBI |
10 ug |
EUR 614 |
pAAVS1-SA-T2A-Neo-CAG-MCS-SV40pA Donor Vector |
AC2302 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-Puro-CAG-MCS-SV40pA Donor Vector |
AC2301 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-HygR-CAG-MCS-SV40pA Donor Vector |
AC2303 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-Neo-SV40pA-MCS-SFFV Donor Vector |
AC2402 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-Neo-CAG-dCas9-VPR-pA Donor Vector |
AC8302 |
ALSTEM |
10 μg |
EUR 805 |
pAAVS1-SA-T2A-Neo-CAG-dCas9-KRAB-pA Donor Vector |
AC7302 |
ALSTEM |
10 μg |
EUR 805 |
pAAVS1-SA-T2A-Neo-CAG-EGFP-SV40pA Control Donor Vector |
AC9312 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-Puro-CAG-EGFP-SV40pA Control Donor Vector |
AC9311 |
ALSTEM |
10 μg |
EUR 665 |
pAAVK-EF1α -MCS-T2A-EGFP AAVanced Cloning and Expression Vector |
AAV526A-1 |
SBI |
10 ug |
EUR 614 |
pAAVK-EF1α -MCS-T2A-Puro AAVanced Cloning and Expression Vector |
AAV527A-1 |
SBI |
10 ug |
EUR 614 |
pAAVK-EF1α –MCS-T2A-mRFP AAVanced Cloning and Expression Vector |
AAV528A-1 |
SBI |
10 ug |
EUR 614 |
pAAVS1-SA-T2A-Puro-SV40pA-EGFP-SFFV Control Donor Vector |
AC9411 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-Puro-CAG-copGFP-SV40pA Control Donor Vector |
AC9321 |
ALSTEM |
10 μg |
EUR 665 |
pAAVS1-SA-T2A-Puro-SV40pA-copGFP-SFFV Control Donor Vector |
AC9421 |
ALSTEM |
10 μg |
EUR 665 |
pAAVK-EF1α-MCS1-CMV-MCS2 AAVanced Cloning and Expression Vector |
AAV503A-1 |
SBI |
10 ug |
EUR 614 |
pAAVK-EF1α-MCS1-CMV-EGFP AAVanced Cloning and Expression Vector |
AAV536A-1 |
SBI |
10 ug |
EUR 614 |
pAAVK-EF1α-MCS1-CMV-Puro AAVanced Cloning and Expression Vector |
AAV537A-1 |
SBI |
10 ug |
EUR 614 |
pAAVK-EF1α-MCS1-CMV-mRFP AAVanced Cloning and Expression Vector |
AAV538A-1 |
SBI |
10 ug |
EUR 614 |
AAVS1 Safe Harbor cDNA/miRNA Donor Vector [pAAVS1D-PGK.MCS-EF1a.copGFPpuro] |
GE602A-1 |
SBI |
10 ug |
EUR 1190 |
pAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-VPR-pA Donor Vector |
AI8902 |
ALSTEM |
10 μg |
EUR 875 |
pAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-KRAB-pA Donor Vector |
AI7902 |
ALSTEM |
10 μg |
EUR 875 |
pAAVS1-SA-T2A-Puro-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector |
AI3901 |
ALSTEM |
10 μg |
EUR 875 |
pAAVS1-SA-T2A-Neo-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector |
AI3902 |
ALSTEM |
10 μg |
EUR 875 |
pAAVS1-SA-T2A-HygR-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector |
AI3903 |
ALSTEM |
10 μg |
EUR 875 |
AAVS1 Safe Harbor Positive Control Donor Vector [pAAVS1D-CMV.RFP-EF1a.copGFPpuro] |
GE603A-1 |
SBI |
10 ug |
EUR 1190 |
pAAVS1-SA-T2A-Puro-CAG-EGFP-SV40pA-SV40pA-MCS-SFFV Donor Vector |
AC4411 |
ALSTEM |
10 μg |
EUR 665 |
Rc3h2 ORF Vector (Rat) (pORF) |
ORF074641 |
ABM |
1.0 ug DNA |
EUR 607.2 |
RC3H2 ORF Vector (Human) (pORF) |
ORF008684 |
ABM |
1.0 ug DNA |
EUR 114 |
RC3H1 ORF Vector (Human) (pORF) |
ORF028827 |
ABM |
1.0 ug DNA |
EUR 486 |
Rc3h1 ORF Vector (Mouse) (pORF) |
ORF055784 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Rc3h2 ORF Vector (Mouse) (pORF) |
ORF055785 |
ABM |
1.0 ug DNA |
EUR 607.2 |
RC3H1-IT1 ORF Vector (Human) (pORF) |
ORF028828 |
ABM |
1.0 ug DNA |
Ask for price |
PAAF1 ORF Vector (Human) (pORF) |
ORF007465 |
ABM |
1.0 ug DNA |
EUR 114 |
PAAF1 ORF Vector (Human) (pORF) |
ORF007466 |
ABM |
1.0 ug DNA |
EUR 114 |
RC3H2 Protein Vector (Rat) (pPM-C-HA) |
PV298564 |
ABM |
500 ng |
EUR 1399.2 |
RC3H2 Protein Vector (Rat) (pPB-C-His) |
PV298562 |
ABM |
500 ng |
EUR 1399.2 |
RC3H2 Protein Vector (Rat) (pPB-N-His) |
PV298563 |
ABM |
500 ng |
EUR 1399.2 |
RC3H2 Protein Vector (Rat) (pPM-C-His) |
PV298565 |
ABM |
500 ng |
EUR 1399.2 |
RC3H2 Protein Vector (Human) (pPM-C-HA) |
PV034735 |
ABM |
500 ng |
EUR 394.8 |
RC3H1 Protein Vector (Human) (pPM-C-HA) |
PV115308 |
ABM |
500 ng |
EUR 973.2 |
RC3H1 Protein Vector (Mouse) (pPM-C-HA) |
PV223136 |
ABM |
500 ng |
EUR 1278 |
RC3H2 Protein Vector (Mouse) (pPM-C-HA) |
PV223140 |
ABM |
500 ng |
EUR 1278 |
RC3H2 Protein Vector (Human) (pPB-C-His) |
PV034733 |
ABM |
500 ng |
EUR 394.8 |
RC3H2 Protein Vector (Human) (pPB-N-His) |
PV034734 |
ABM |
500 ng |
EUR 394.8 |
RC3H2 Protein Vector (Human) (pPM-C-His) |
PV034736 |
ABM |
500 ng |
EUR 394.8 |
RC3H1 Protein Vector (Human) (pPB-C-His) |
PV115306 |
ABM |
500 ng |
EUR 973.2 |
RC3H1 Protein Vector (Human) (pPB-N-His) |
PV115307 |
ABM |
500 ng |
EUR 973.2 |
RC3H1 Protein Vector (Human) (pPM-C-His) |
PV115309 |
ABM |
500 ng |
EUR 973.2 |
RC3H1 Protein Vector (Mouse) (pPB-C-His) |
PV223134 |
ABM |
500 ng |
EUR 1278 |
RC3H1 Protein Vector (Mouse) (pPB-N-His) |
PV223135 |
ABM |
500 ng |
EUR 1278 |
RC3H1 Protein Vector (Mouse) (pPM-C-His) |
PV223137 |
ABM |
500 ng |
EUR 1278 |
RC3H2 Protein Vector (Mouse) (pPB-C-His) |
PV223138 |
ABM |
500 ng |
EUR 1278 |
RC3H2 Protein Vector (Mouse) (pPB-N-His) |
PV223139 |
ABM |
500 ng |
EUR 1278 |
RC3H2 Protein Vector (Mouse) (pPM-C-His) |
PV223141 |
ABM |
500 ng |
EUR 1278 |
RC3H1-IT1 Protein Vector (Human) (pPM-C-HA) |
PV115312 |
ABM |
500 ng |
Ask for price |
RC3H1-IT1 Protein Vector (Human) (pPB-C-His) |
PV115310 |
ABM |
500 ng |
Ask for price |
RC3H1-IT1 Protein Vector (Human) (pPB-N-His) |
PV115311 |
ABM |
500 ng |
Ask for price |
RC3H1-IT1 Protein Vector (Human) (pPM-C-His) |
PV115313 |
ABM |
500 ng |
Ask for price |
PAAF1 Protein Vector (Human) (pPM-C-HA) |
PV029859 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPM-C-HA) |
PV029863 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPB-C-His) |
PV029857 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPB-N-His) |
PV029858 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPM-C-His) |
PV029860 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPB-C-His) |
PV029861 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPB-N-His) |
PV029862 |
ABM |
500 ng |
EUR 394.8 |
PAAF1 Protein Vector (Human) (pPM-C-His) |
PV029864 |
ABM |
500 ng |
EUR 394.8 |
RC3H2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
LV639829 |
ABM |
1.0 ug DNA |
EUR 1626 |
RC3H2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC) |
LV639833 |
ABM |
1.0 ug DNA |
EUR 1626 |
RC3H2 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a) |
LV639834 |
ABM |
1.0 ug DNA |
EUR 1626 |
RC3H1-IT1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
LV742619 |
ABM |
1.0 ug DNA |
Ask for price |
RC3H1-IT1 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
LV742623 |
ABM |
1.0 ug DNA |
Ask for price |
RC3H1-IT1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
LV742624 |
ABM |
1.0 ug DNA |
Ask for price |
PAAF1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
LV713073 |
ABM |
1.0 ug DNA |
EUR 379.2 |
Host cell variations to permit the intracellular persistence of useful micro organism are discovered together with proof for the microbial manipulation of host cells, however the mobile mechanisms of useful bacterial infections usually are not nicely understood. Expected closing on-line publication date for the Annual Review of Cell and Developmental Biology, Volume 37 is October 2021.