International Biology Olympiad

Bone marrow mesenchymal stem cells-derived exosomes for penetrating and focused chemotherapy of pancreatic most cancers   Pancreatic ductal adenocarcinoma (PDAC) is among the most intractable malignancy, with an solely 6% 5-year relative survival price. The dismal therapeutic impact is attributed to the chemotherapy resistance and distinctive pathophysiology with considerable inflammatory cytokines and irregular hyperplasia of extracellular matrix …

Exosome as a Natural Gene Delivery Vector for Cancer Treatment   Background: Current gene remedy vectors are viral vectors, non-viral vectors and bacterial vectors that are used for most cancers remedy, however there are particular security issues and stability points of those standard vectors. Exosomes are the vesicles of measurement 40-100 nm secreted from multivesicular our bodies …

Propofol Affects Non-Small-Cell Lung Cancer Cell Biology By Regulating the miR-21/PTEN/AKT Pathway In Vitro and In Vivo   Background: Propofol is a standard sedative-hypnotic drug historically used for inducing and sustaining common anesthesia. Recent research have drawn consideration to the nonanesthetic results of propofol, however the potential mechanism by which propofol suppresses non-small-cell lung most cancers (NSCLC) development has not …

Recent advances in synthetic biology-enabled and natural whole-cell optical biosensing of heavy metals   Numerous scientific works have been printed on whole-cell heavy metallic biosensing based on optical transduction. The advances in the software program of biotechnological devices not solely have repeatedly improved the sensitivity, selectivity, and detection range for biosensors however moreover have concurrently unveiled new …